FIELD: organic chemistry. SUBSTANCE: product: (1′R,5′R)-3′-aza-1′- (2-amino-1,6-dihydro-6-oxopurinyl-9) -3′-deoxy- 3′- azidonaphthalene-1-sulfamido) -hexopyranosyl-6′-triphosphate trilithium salts, yield is 58-63%, empirical formula is C20H26Li3N10O16P3S·2H2O. Reagent 1: 4- or 5-azidonaphthalene-1-sulfonylhydrazine. Reagent 2: oxoguanosine-5′-triphosphate sodium salt, in the presence of lithium-acetate buffer. Reaction condition: in dioxane medium, at pH 4.5-5. EFFECT: improved method of synthesis. 2 tbl
| Title |
Year |
Author |
Number |
| AZIDONAPHTHALENE -1-SULFONYLHYDRAZINES AS SEMIPRODUCTS FOR SYNTHESIS OF (1′R,5′R)-3′-AZA-1′- (2-AMINO-1,6-DIHYDRO-6-OXOPURINYL-9)-- 3′-DEOXY- 3′-(AZIDONAPHTHALENE-1-SULFAMIDO)-HEXOPYRANOSY- L-6′- TRIPHOSPHATES TRILITHIUM SALTS AS SPECIFIC PHOTOACTIVATED IRREVERSIBLE RNA-POLYMERASE INHIBITORS |
1991 |
- Khropov Ju.V.
- Mishin A.A.
- Seliverstov V.O.
- Kulagin S.V.
- Kochetkov S.N.
|
RU2036903C1 |
| 4-AZIDONAPHTHALENE-1-SULFONYLCHLORIDE AS SEMIPRODUCT FOR SYNTHESIS OF (1′R,5′R) -3′-AZA-1′ -(2-AMINO-1,6-DIHYDRO-6-OXOPURINYL-9)-- 3′-DEOXY-3′- (4-AZIDONAPHTHALENE-1-SULFAMIDO) HEXOPYRANOSYL-- 6′-TRIPHOSPHATE TRILITHIUM SALT AS SPECIFIC PHOTOACTIVATED IRREVERSIBLE RNA-POLYMERASE INHIBITOR |
1991 |
- Kulagin S.V.
- Seliverstov V.O.
- Khropov Ju.V.
- Mishin A.A.
- Kochetkov S.N.
|
RU2036902C1 |
| HALOID-CONTAINING 3'-AMIDODERIVATIVES OF (1'R,5'R)-3' -AZA-1'-(2-AMINO -1,6-DIHYDRO -6-OXOPURINYL-9) -3'-DEOXYPYRANOSIDE AS SPECIFIC IRREVERSIBLE FLUORESCENT INHIBITORS OF RNA-POLYMERASE |
1991 |
- Khropov Ju.V.
- Baranova L.A.
- Tunitskaja V.L.
- Kochetkov S.N.
|
RU2039065C1 |
| LITHIUM SALTS OF (I'R,5'R)-3'-AZA-3'-(AZIDONAPHTHALINE-1- SULFAMIDO)-1'-(6-AMINOPURINYL-9)-3'-DEOXYHEXOPIRANOZYL- 6'-DI-OR TRIPHOSPHATES AS SPESIFIC PHOTOACTIVATED IRREVERSIBLE INHIBITORS OF Na, K-ADENOSINE TRIPHOSPHATASE |
1997 |
- Khropov Ju.V.
- Mishin A.A.
- Seliverstov V.O.
- Kulagin S.V.
- Lopina O.D.
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RU2130943C1 |
| SALTS OF (1'R, 5'R)-3'-AZA-1'(6-AMINOPURINYL-9)-3'- DEOXYHEXOPYRANOSYL-6'-DIPHOSPHATE 3'-AMIDODERIVATIVES AS SPECIFIC FLUORESCENT INHIBITORS OF MYOSINIC ADENOSINE-5'- TRIPHOSPHATASE |
1997 |
- Baranova L.A.
- Khropov Ju.V.
- Pron'Ko G.M.
- Petushkova E.V.
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RU2131435C1 |
| 5′-BENZOYLGUANOSINE DERIVATIVES AS SPECIFIC IRREVERSIBLE INHIBITORS OF RNA-POLYMERASE |
1990 |
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- Pinchuk N.Ja.
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RU2035468C1 |
| INHIBITOR OF NO-DEPENDENT ACTIVATION OF GUANYLATE CYCLASE SOLUBLE FORM |
2001 |
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RU2188865C1 |
| 5-FLUOROSULFONYL-BENZOYL DERIVATIVES OF URIDINE FOR SPECIFIC NON-REVERSIBLE INHIBITION OF GLYCOGENE SYNTHESASE |
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SU1122671A1 |
| 2-(2-AMINO-1,6-DIHYDRO-6-OXOPURIN-9-YL)METOXY-3-HYDROXY- 1-PROPANYL-L-VALINATE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD OF PREPARING THEREOF, PHARMACEUTICAL COMPOSITION AND HYDROXY AND/OR AMINO PROTECTED 2-(2- AMINO-1,6-DIHYDRO-6-OXOPYRIN-9-YL) METHOXY-3-HYDROXY-1- PROPANYL-L-VALINATE |
1995 |
- Dzhon Dzh.Nestor
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RU2133749C1 |
| METHOD FOR INHIBITION OF RNA-POLYMERASE FERMENT ACTIVITY |
2012 |
- Voloshin Jan Zigfridovich
- Novikov Valentin Vladimirovich
- Varzatskij Oleg Anatol'Evich
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