1-HEXYL-4- PHENYL-4-BIPERIDINE CARBOXAMIDE N-SUBSTITUTED DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PROCESS FOR PREPARING THEREOF Russian patent published in 1995 - IPC

Abstract RU 2039043 C1

FIELD: organic chemistry. SUBSTANCE: 1-hexyl-4-phenyl 4- piperidinecarboxamide N-substituted derivative of the formula: CH2CH2N(C4H9)CH2CH2C(C6H5)CONR1R2 wherein R1 and R2 are the same as different and each represents C1-C4-alkyl, or R1 and R2 together form a (CH2)5 chain, or one of R1 and R2 is hydrogen and the other is C1-C4-alkyl. Reagent 1: 1-hexyl- 4-phenyl-4-piperidinylcarboxylic acid ethyl ester. Reagent 2: R1NH3. Reaction conditions: a compound of the general formula is obtained wherein R2 is hydrogen. EFFECT: improved properties of the title compounds. 6 cl, 2 tbl

Similar patents RU2039043C1

Title Year Author Number
PIPERIDINE DERIVATIVES, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL PREPARATION BASED ON THEREOF 1995
  • Anna-Lena Ask
  • Lars-Inge Ol'Sson
  • Rune Sandberg
RU2145599C1
METHOD FOR SYNTHESIS OF FORMOTEROL OR ITS DERIVATIVES 1991
  • Jan Villiam Trofast[Se]
  • Ehdib Jakupovits[Yu]
  • Lena Katarina Monsson[Se]
RU2079486C1
S-ENANTIOMER OF SUBSTITUTED 2-AMINOTETRALINE, METHODS OF ITS SYNTHESIS AND PHARMACEUTICAL COMPOSITION SHOWING PROPERTY OF 5- RECEPTOR ANTAGONIST 1990
  • Uli Khaksell[Se]
  • Sven-Ehrik Khillver[Se]
RU2086537C1
DERIVATIVES OF 3,3′-DITHIOBIS-(PROPIONIC ACID) OR THEIR STEREOISOMERS AND COMPOSITION SHOWING IMMUNOMODULATING ACTION 1991
  • Karl-Magnus Aleksander Andersson[Se]
  • Sten Khokan Aksel' Bergstrand[Se]
  • Anders Rudol'F Khall'Berg[Se]
  • Bengt Uljuf Sehrnstrand[Se]
  • Per Anders Sigvard Tunek[Se]
RU2041208C1
NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND INTERMEDIATE SUBSTANCES 1997
  • Pelkman Bendzhamin
  • Roberts Ehdvard
RU2193030C2
METHOD OF SYNTHESIS OF ANTAGONISTS OF NMDA (N-METHYL-D-ASPARTATE) 1997
  • Kharris Alan Richard
RU2190597C2
PHENYLETHYL- AND PHENYLPROPYLAMINE COMPOUNDS, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL PREPARATION 1994
  • Stefan Bengtsson
  • Sven Khell'Berg
  • Nina Mokhell'
  • Lian Zhang
  • Gerd Khall'Nemo
  • Dejvid Dzhekson
  • Bengt Ul'Ff
RU2133735C1
DERIVATIVES OF CHROMAN OR THIOCHROMAN AND METHODS OF THEIR SYNTHESIS (VARIANTS) 1990
  • Lars-Gjunnar Larsson[Se]
  • Rol'F Noren[Se]
  • Ljusi Anna Reni[Se]
  • Svante Bertil Ross[Se]
  • Daniel' Dungann Sonn[Se]
  • B'Ern Ehrik Svensson[Se]
  • Set Olov Torberg[Se]
RU2092483C1
METHYLISOPROPYL-[(3-N-PROPOXYPHENOXY)ETHYL]AMINE OR ITS PHARMACEUTICALLY ACCEPTABLE SALT, METHODS OF ITS SYNTHESIS (VARIANTS), PHARMACEUTICAL COMPOSITION, METHOD OF TOPICAL ANESTHESIA 1996
  • Sandberg Rune
RU2193555C2
NOVEL OPIOIDO-LIKE PEPTIDES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION 1996
  • Vuji Vang
RU2165432C2

RU 2 039 043 C1

Authors

Anna-Lena Ask[Se]

Rune Sandberg[Se]

Dates

1995-07-09Published

1992-06-19Filed