FIELD: organic chemistry. SUBSTANCE: product: (-)-5-fluoro-8-hydroxy-2-(dipropylamino)tetraline hydrobromide, yield is 85%, m. p. is 186-187 C, optical rotation is -69.3 (c = 1). (+)-5-Fluoro-8-hydroxy-2-(dipropylamino)tetraline hydrobromide, yield is 69%, m. p. is 186-187 C, optical rotation is +69.4 (c = 0.9). Synthesized compounds were used as preparations showing therapeutic activity with respect to the central nervous system. EFFECT: improved method of synthesis. 8 cl, 1 tbl
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1990 |
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