DERIVATIVES OF QUINAZOLINE- OR BENZODIAZEPINE CARBOXYLIC ACID AND THEIR SALTS Russian patent published in 1995 - IPC

FIELD: organic chemistry. SUBSTANCE: products: derivatives of quinazoline- or benzodiazepine carboxylic acid of the formula (I) -CH₂-CH₂- where R hydrogen, halogen, lower alkyl or lower alkoxy-group; A a group C=O or C= S; B a group R₁, -CHR where R₂ hydrogen, lower alkyl or hydroxyl; X oxygen or group NH; Y a group of the formula (II) Q₁ where Q₂ lower alkyl; q 2 or 3, and their salts showing antimuscarinic activity. Reagent 1: compounds of the formula (III) . Reagent 2: compounds of the formula (IV) where and splitting off groups. Reaction conditions: at 20-100 C, in the medium of aprotonic solvent, in the presence of acid acceptor. Synthesized compounds were used in pharmaceutical industry. EFFECT: improved method of synthesis. 3 cl, 1 tbl