FIELD: organic chemistry. SUBSTANCE: product - derivatives of R(-)-3-quinuclidinol of the formula (I) where R - non- or branched lower alkyl, C3-C7-cyclo-C1-C2-alkyl; R1 - hydrogen or non- or branched lower alkyl or acyl of the formula: R2-C(O)- where R2 - hydrogen or non- or branched lower alkyl; A - C5-C7-cycloalkyl, phenyl, thienyl, pyridyl; X - anion of in- or organic acid; Y and Z are both oxygen or one of their is oxygen or sulfur; m and m′ = 0 or 1; n = 1-3; p = p′ = 1, p or and p′ - are different and 0 or 1. A-group and 3-quinuclidine ester group are in heminal position. Synthesized compounds were used in pharmacology. EFFECT: improved method of synthesis.
| Title |
Year |
Author |
Number |
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1992 |
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|
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1993 |
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|
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|
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1992 |
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1990 |
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- Dzhordzho Long[It]
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|
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