METHOD OF SYNTHESIS OF 5-AMINO-2,4,6-TRIIODO- 1,3-BENZOCARBOXYLIC ACID DERIVATIVES Russian patent published in 1995 - IPC

Abstract RU 2046795 C1

FIELD: organic chemistry. SUBSTANCE: product: derivatives of 5-amino-2,4,6-triiodo-1,3-benzocarboxylic acid of the formula (I) where y simple bond or -CH2-CH2-,CH2-O,-OCH2,-CH2 or oxygen; R1 and R2 are different or similar group: HO-CH2-CH(OH)-CH2-;; [HOCH2]CH;-(CH2)2OH;CH-CH2(OH)-CH(CH2OH)-; HO-CH2-CH(OH)-CH(CH2OH)-;R3-R4(3) and R hydrogen, methyl, ethoxyl; R5-R6 and R hydrogen, alkyl, hydroxyl, methoxyl, ethoxyl. Reagent 1: compounds of the formula (II) . Reaction conditions: cyclization of reagent 1. Synthesized compounds were used in medicine. EFFECT: improved method of synthesis. 5 tbl

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RU 2 046 795 C1

Authors

Ramachandran S.Ranganatan[Us]

Tangavel Arunachalam[In]

Ehdmund R.Marinelli[Us]

Radkhakrishna Pillai[In]

Dates

1995-10-27Published

1990-11-28Filed