FIELD: pharmaceutical industry. SUBSTANCE: milt is homogenized, the precipitate is separated, treated with a detergent and concentrated salt solution and after incubation is subjected to ultrasound using a typical set of insonification equipment and conditions that allow obtaining DNA with a molecular weight of from 0,6×106 of 1,5×106 Da, the protein and the detergent are separated either by filtration through kieselguhr and subsequently by fine filtration, or by microfiltration through filtrate is concentrated on a ultrafiltration module at a pressure of 0.2 to 0.8 atm, subjected to diafiltration and once again treated with a molecular weight of from 2,5×105 to 6,0×105 Da, the latter is precipitated with ethanol from the solution and the precipitate is dried to constant weight. EFFECT: improved properties of the title product.
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Authors
Dates
1995-08-20—Published
1993-05-31—Filed