FIELD: organic chemistry. SUBSTANCE: tetrahydroacridine derivative of general formula (I) wherein Y is CHOH or C=0; R3 is OH or O-CO-APK. Geometric and optical isomers, N-oxides and acid addition salts thereof are prepared either by reductive cyclization of compound of formula (II) followed, if desires, by treating the resulting compound with alkanic acid anhydride followed, if desired, by treating the resulting compound with alkali metal alumohydride, or by oxidative detachment of -Si(R10)2R11 in compound of general formula (III) followed, if desired, by reducing the resulting, compound with alkali metal trialkylboron hydride. EFFECT: improved properties of the pharmaceutical composition. 8 cl, 1 dwg, 2 tbl
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1992 |
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| SUBSTITUTED TETRAHYDRO-, OR HEXAHYDROCYCLOPENT/B/ INDOLES OR THEIR PHARMACEUTICALLY ACCEPTABLE ADDITIVE SALTS AND METHOD FOR THEIR PRODUCTION |
1992 |
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| BENZISOTHIAZOLE- OR BENZISOXAZOLE-3-CARBOXAMIDES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION SHOWING ANTIPSYCHOTIC ACTIVITY |
1992 |
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1992 |
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RU2074181C1 |
| GALANTAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION |
1994 |
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RU2109743C1 |
| METHOD OF SYNTHESIS OF AMINOCARBONYLCARBAMATES |
1990 |
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RU2069664C1 |
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RU2113438C1 |
