METHOD FOR PRODUCTION OF CARBOXYMETHYL ETHER OF CHITOSAN Russian patent published in 1995 - IPC

Abstract RU 2044741 C1

FIELD: chemical industry, medicine, pharmaceutical and cosmetic industries. SUBSTANCE: chitin is treated by sodium hydroxide and monochloroacetic acid (or by its salt), molar ratio of said compounds being 1:(2.6-8.4): (2.3-4). The process is carried out at 66-200 C and pressure 0.2-50 mPa in extruder having two screws, shear stress being 0,3-3H/mm2. Said monochloroacetic acid or its salt are added in solid state or as solution in isopropyl alcohol. Mentioned above treatment of chitin may be carried out at 80-120 C simultaneously with adding or initially chitin may be treated by sodium hydroxide at 8-200 C, then monochloroacetic acid or its salt are added and further treatment takes place at 60-120 C. Sodium salt of monochloroacetic acid is preferred. Preferred ratio of chitin:NaOH:sodium salt of monochloroactetic acid is 1:(2.6-4.4):(2.3-4.0). EFFECT: improves efficiency of the method. 4 cl

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RU 2 044 741 C1

Authors

Enikolopov N.S.

Rogovina S.Z.

Akopova T.A.

Zelenetskij S.N.

Vikhoreva G.A.

Dates

1995-09-27Published

1992-07-20Filed