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(19)

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2 045 526

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(51)

IPC

(21) (22)

Application

4742319/04, 1989-10-20

(22)

Actual filing date

1989-10-20

(45)

Published

1995-10-10

(72)

Inventor

Ehndrju Dzhordzh Brjuster[Gb]Dzhordzh Robert Braun[Gb]Alan Vellington Faull[Gb]Redzhinal'D Dzhessap[Gb]Majkl Dzhejms Smiterz[Gb]

(73)

Holder

Imperial Kemikal Indastriz Pls

DERIVATIVES OF 1,3-DIOXANE ALKENOIC ACID Russian patent published in 1995 - IPC

Abstract RU 2045526 C1

FIELD: organic chemistry. SUBSTANCE: reaction conditions: process is carried out in the presence of acid; active form is used if optically active form of the end product is synthesized. Synthesized compounds were used in medicine as an inhibitor of thromboxane synthase catalyzing formation of arachidonic acid metabolite, and thromboxane-antagonists, for treatment of ischemic heart disease, cerebro-vascular disease system or/and inflammation. EFFECT: improved method of synthesis. 2 tbl

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RU 2 045 526 C1

Authors

Ehndrju Dzhordzh Brjuster[Gb]

Dzhordzh Robert Braun[Gb]

Alan Vellington Faull[Gb]

Redzhinal'D Dzhessap[Gb]

Majkl Dzhejms Smiterz[Gb]

Dates

1995-10-10—Published

1989-10-20—Filed