FIELD: medicine. SUBSTANCE: method involves immobilizing an experimental animal (guinea pig) for 12-13 h, giving it nothing to eat during 23-24 h and then intraperitoneally administering blood serum taken from a patient suffering from infantile cerebral paralysis, the serum being mixed with incomplete Freund adjuvant in the proportion of 1:1. The mixture is administered at a dose of 57 g of the mixture per 100 g of animal body weight three times a day each fourth day. Clinical symptoms of paralysis with trophic changes are developed at the fifteenth-seventeenth day when counted from the first day the mixture is administered. EFFECT: enhanced effectiveness in reproducing clinical course of disease development. 1 dwg
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Authors
Dates
1996-03-27—Published
1994-02-18—Filed