Show metadata Hide metadata

(19)

(11)

2 057 755

(13)

(51)

IPC

(21) (22)

Application

93046196/04, 1993-09-29

(22)

Actual filing date

1993-09-29

(45)

Published

1996-04-10

(72)

Inventor

Rabinovich I.M.Kaljuzhnyj I.A.Mezentseva V.D.Lisetskaja N.L.Fisun L.N.Kalnina M.M.

(73)

Holder

Aktsionernoe Kurganskoe Obshchestvo

METHOD FOR PRODUCTION OF AMPICILLLIN Russian patent published in 1996 - IPC

Abstract RU 2057755 C1

FIELD: medicine. SUBSTANCE: glace suspension of salt of 6-aminopenicillanic acid in aqueous-acetone solution is acetylated. This process is carried out with the help of acetone solution of mixed anhydride of N-substituted D-(-)-α-aminoacetic acid and ester of chlorocarbonic acid, said solution being cooled to (-10)-(-30) C. Thus obtained N-substituted ampicillin is affected by hydrolysis followed by isolation of desired product. EFFECT: improves efficiency of method. 2 cl

Similar patents RU2057755C1

Title	Year	Author	Number
	0	Povarov Leonard Sergeevich Rabinovich Meri Solomonovna	SU516692A1
METHOD OF SYNTHESIS OF UREIDO-DERIVATIVES OF PENICILLIN OR CEPHALOSPORIN	1990	Zinchenko E.Ja. Lesovaja Z.I. Mezentsev A.S.	SU1707959A1
METHOD OF PRODUCING SODIUM SALT OF 6-[3-(2-CHLORO-6-FLUOROPHENYL)-5-METHYLISOXAZOLE-4-CARBAMINO]-PENICILLANIC ACID	2011	Savel'Ev Evgenij Aleksandrovich Kovalevskaja Anna Leonidovna Semenov Pavel Anatol'Evich	RU2457211C1
METHOD OF SYNTHESIS OF BETA-LACTAM DERIVATIVE	1991	Svenn Gunnar Kosgord Ulla Vejtland	RU2136759C1
METHOD OF ISOLATION OF PHENOXYMETHYLPENICILLINIC ACID	1994	Ustjuzhanina I.Ju. Uzhegov A.V.	RU2081174C1
METHOD FOR PRODUCTION OF SODIUM SALT OF 6-(3-PHENYL-5-METHYLISOXASOL-4-CARBAMINO)-PENICILLANIC ACID	1991	Savel'Ev E.A. Loseva L.D. Guss F.V. Vinogradov E.A.	RU2043359C1
METHOD OF ISOLATING OXACILLINE SODIUM SALT	1997	Rabinovich I.M.	RU2137775C1
METHOD OF OBTAINING SODIUM SALT OF 6-[3-(2,6-DICHLROPHENYL)-5METHYL-ISOXAZOLE-4-CARBAMINO]-PENICILLANIC ACID	2006	Savel'Ev Evgenij Aleksandrovich Gomzhin Andrej Mikhajlovich	RU2356904C2
METHOD FOR ISOLATING OXACILLIN SODIUM SALT FROM AQUEOUS AND AQUEOUS-ORGANIC MEDIA	2004	Rabinovich Il'Ja Mikhajlovich Pshenichnikov Vitalij Georgievich	RU2272041C1
METHOD OF PREPARING 6-(3-PHENYL-5-METHYLISOXAZOL-4- CARBAMINO)PENICILLANIC ACID SODIUM SALT	2002	Savel'Ev E.A. Lysova T.N. Fadeeva A.E.	RU2221801C1

RU 2 057 755 C1

Authors

Rabinovich I.M.

Kaljuzhnyj I.A.

Mezentseva V.D.

Lisetskaja N.L.

Fisun L.N.

Kalnina M.M.

Dates

1996-04-10—Published

1993-09-29—Filed