FIELD: biotechnology, enzymology. SUBSTANCE: invention is related with directed increase of synthesis of certain hydrolase complex and increased their secretion from cells. Nutrient medium for cultivation of Aspergillus oryzae contains starch-containing raw (carbohydrate source), necessary mineral salts of potassium phosphate and, additionally, protein sources and detergents at the following concentration, wt.-%: starch-containing raw 3-4; wheat bran 1-4; food, baker or residual brewery yeast, or protein-vitamin concentrate 0.5-1.5; proxanol 0.01-0.03 or phthalate ("ЦС-21") 0.05-0.15. EFFECT: enhanced quality and effectiveness of medium. 3 cl, 4 tbl
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