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2 065 308

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C1

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IPC

(21) (22)

Application

92006762/13, 1992-11-17

(22)

Actual filing date

1992-11-17

(45)

Published

1996-08-20

(72)

Inventor

Supotnitskij M.V.Maslov A.V.Seroglazov V.V.Kozhukhov V.V.

(73)

Holder

Nauchno-Issledovatel'Skij Institut Mikrobiologii Ministerstva Oborony Rossijskoj Federatsii

METHOD OF SPECIFIC PROPHYLAXIS OF MELIODOSIS Russian patent published in 1996 - IPC

Abstract RU 2065308 C1

FIELD: biotechnology, microbiology. SUBSTANCE: protein exhibiting pore-forming function in cellular wall of meliodosis pathogen and purified from cytoplasmic proteins and peptidoglycan is administrated to meliodosis-sensitive animal by subcutaneous route at dose 880-7000 mcg/mg animal mass. Immunization is carried out by schedule that is experimentally adopted to each animal species. Protective effect estimation is carried out by subcutaneous infection of animals with virulent culture of meliodosis microorganism. Method provides survival 100% white rats infected with subcutaneous dose ID50 of agar culture of high-virulent strain of Pseudomonas pseudomallei CN-141. EFFECT: improved method of prophylaxis. 2 tbl

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RU 2 065 308 C1

Authors

Supotnitskij M.V.

Maslov A.V.

Seroglazov V.V.

Kozhukhov V.V.

Dates

1996-08-20—Published

1992-11-17—Filed

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