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2 072 996

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IPC

(21) (22)

Application

93004535/04, 1993-02-02

(22)

Actual filing date

1993-02-02

(45)

Published

1997-02-10

(72)

Inventor

Dzhordzh Bernard Bouder[Us]Vill'Jam Dzhozef Ehlkhardt[Us]Dzheral'D Berr Grindi[Us]Dzhon Ehldon Tot[Us]Dzhon Frederik Vorzalla[Us]Dzhon Lajl Zimmermann[Us]

(73)

Holder

Ehli Lilli Ehnd Kompani

N-[((3,4-DICHLOROPHENYL)-AMINO)-CARBONYL]-2,3-DIHYDROBENZOFU- -RAN-5-SULFONAMIDE OR ITS PHARMACEUTICALLY ACCEPTABLE SALT, METHOD OF ITS SYNTHESIS AND COMPOSITION SHOWING ANTITUMOR ACTION Russian patent published in 1997 - IPC

Abstract RU 2072996 C1

FIELD: organic chemistry. SUBSTANCE: product: N-[((3,4-dichlorophenyl)-amino)-carbonyl]-2,3-dihydrobenzofu- -ran-5-sulfonamide or pharmaceutically acceptable salt, method of synthesis and composition showing antitumor action. Reagent 1: compound of the formula (II) where Y - NCO-group. Reagent 2: compound of the formula (III) where X - -NCO or NH₂-group. Amount of an active component in composition is 5-500 mg per a single dose. Compound (I) inhibits tumor growth by 81-100%. Synthesized compound is used in oncology. EFFECT: improved method. 1 tbl, 4 cl

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RU 2 072 996 C1

Authors

Dzhordzh Bernard Bouder[Us]

Vill'Jam Dzhozef Ehlkhardt[Us]

Dzheral'D Berr Grindi[Us]

Dzhon Ehldon Tot[Us]

Dzhon Frederik Vorzalla[Us]

Dzhon Lajl Zimmermann[Us]

Dates

1997-02-10—Published

1993-02-02—Filed