CELLULOSE DIETHYLAMINOETHYL ETHER AS SORBENT FOR RECOVERY AND PURIFICATION OF ENZYME PREPARATIONS AND PROCESS FOR PURIFICATION OF STREPTOKINAZE Russian patent published in 1997 - IPC

Abstract RU 2076870 C1

FIELD: microbiology. SUBSTANCE: cellulose diethylaminoethyl ether of general formula: (C2H5)2NC2H4-OR wherein R is matrix of granular microspherical cellulose which is prepared by dissolving microcrystalline cellulose in aqueous solution of calcium rodanide, dispersing the resulting solution in transformer oil and recovering by treatment of the resulting mixture with hexane followed by washing the recovered product with hexane, acetone and water. The claimed compound is used as sorbent for recovery and purification of enzyme preparations, more particularly for purification of streptokinase. EFFECT: more efficient purification process. 3 cl, 2 tbl

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RU 2 076 870 C1

Authors

Boldyrev Aleksandr Georgievich

Zajtsev Petr Ivanovich

Stepanov Valerij Vladimirovich

Moloshnikov Vladimir Alekseevich

Fedorova Natal'Ja Mikhajlovna

Kaloshin Valentin Genrikhovich

Parr Galina Semenovna

Borisova Valentina Alekseevna

Andreeva Teodora Vasil'Evna

Dates

1997-04-10Published

1993-02-17Filed