DERIVATIVES OF QUINOLINE OR ITS SALTS, METHOD FOR THEIR PRODUCTION, SOLID PHARMACEUTICAL COMPOSITION Russian patent published in 1997 - IPC

FIELD: medicine. SUBSTANCE: desired derivatives have formula given in specification where R¹ is halogen, nitro, azido, alkoxyl C₁-C₈, acyl C₁-C₈, alkyl C₁-C₈, substituted or unsubstituted by hydroxyl or by C₁-C₆ alkyl alkenyl C₁-C₆, nitrogen-containing heterocycle; R² is cycloalkyl C₃-C₁₂;; R³ is -OR⁴, -NH-SO₂-R⁵ where R⁴ is H, alkyl C₁-C₈; R⁵ is aryl C₆-C₁₀ being substituted or unsubstituted. Compound having formula given in specification where W is benzyl or tert-butyl, R^4′=R⁴ except hydrogen is used as reagent 1. Compound having formula I given in specification (where Y is halogen) is used as reagent 2. Reaction is carried out in the medium of solvent, it is followed if it is necessary by saponification of thus obtained product. EFFECT: improved quality of desired product. 5 cl, 8 tbl