DERMATAN SULFATE OR ITS SALT, ANTITHROMBOTIC AGENTS, METHOD OF PROPHYLAXIS AND TREATMENT OF THROMBOSIS, METHOD OF PROPHYLAXIS OR TREATMENT OF DISSEMINATED INTRAVASCULAR COAGULATION SYNDROME, METHOD OF MYOCARDIUM INFARCTION TREATMENT Russian patent published in 2000 - IPC

Abstract RU 2153506 C2

FIELD: medicine. SUBSTANCE: invention describes dermatan sulfate or its salt with intrinsic viscosity value 0.8 (100 ml/g) or above using 0.2 M sodium chloride solution as solvent at 30 ± 0.1 C. Indicated dermatan sulfate has 0.15% or less of heparin or heparan sulfate determined by method involving treatment with enzymes that cleave heparin or heparan sulfate and high pressure liquid chromatography. Dermatan sulfate has also 0.07% or less of heparin or heparan sulfate determined by inhibitory effect of active factor in the presence of antithrombin-III using heparin isolated from cow guts as standard substance or 0.05% of less of heparin or heparan sulfate determined by inhibitory effect of active factor-II in the presence of antithrombin-III using heparin isolated from cow guts as standard substance. Dermatan sulfates or their salts are antithrombotic agents that inhibit thrombus distribution and stimulate their lysis. Invention describes also antithrombosis agents, method of prophylaxis or treatment of patients with disseminated intravascular coagulation syndrome and method of treatment of patients with myocardium infarction. EFFECT: improved method of prophylaxis and treatment, valuable medicinal properties. 18 cl, 8 tbl, 6 dwg, 9 ex

Similar patents RU2153506C2

Title Year Author Number
PHOTOCONSOLIDATED DERIVATIVE OF GLYCOSEAMINOGLYCAN, CROSS- -LINKED DERIVATIVE OF GLYCOSEAMINOGLYCAN AND METHODS OF THEIR SYNTHESIS, COMPOSITION FOR MEDICINAL USE, METHOD OF PREVENTION OF CELLULAR AND TISSUE ADHESION 1993
  • Takekhisa Matsuda
  • Minoo Dzh.Mogkhaddam
  • Katsukijo Sakurai
RU2139886C1
AGENT ENHANCING ANTI-INFLAMMATORY EFFECT OF IMMUNODEPRESSANT (VERSIONS), METHOD OF ENHANCEMENT OF ANTI-INFLAMMATORY EFFECT OF IMMUNODEPRESSANT, METHOD OF INFLAMMATION TREATMENT 1996
  • Kiogasima Mamoru
  • Asari Akira
RU2176509C2
THROMBOLYTIC AGENTS 1995
  • Khirojuki Utijama
  • Masakhiro Ivaki
RU2142799C1
CHONDROITINASE, METHOD OF ITS PREPARING AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF 1993
  • Nobukazu Khasimoto
  • Khideo Motizuki
  • Akio Khamai
  • Siniti Isikava
  • Misako Torikai
  • Isao Mijati
RU2144833C1
SUCCINIC ACID DERIVATIVES, SUCCINIC ACID-POLYSACCHARIDE DERIVATIVE, METHOD OF PREPARING SUCCINIC ACID-GLYCOSAMINOGLYCANE DERIVATIVE, METHOD OF PREPARING SUCCINIC ACID-POLYAMINOSACCHARIDE DERIVATIVE, AND METHOD OF PREPARING CROSS- LINKED SUCCINIC ACID-POLYSACCHARIDE DERIVATIVE 1995
  • Mitinori Vaki
  • Kendzi Mijamoto
  • Josikhiro Motani
RU2169136C2
POLYPEPTIDES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITION 1992
  • Nobutaka Fudzii[Jp]
  • Naoki Jamamoto[Jp]
  • Akiesi Matsumoto[Jp]
  • Mitinori Vaki[Jp]
RU2083589C1
METHOD OF INHIBITING THROMBUS FORMATION AND ACCELERATION OF FIBRINOLYSIS WITH DNA APTAMERS INHIBITING ACTIVITY OF THROMBIN IN EXPERIMENT 2014
  • Dobrovol'Skij Anatolij Borisovich
  • Mazurov Aleksej Vladimirovich
  • Spiridonova Vera Alekseevna
RU2559545C1
FRACTION OF KERATANSULFATE OLIGOSACCHARIDES AND PHARMACEUTICAL PREPARATION CONTAINING THEREOF 1995
  • Marujama Khirosi
  • Morikava Kijosi
  • Tavada Akira
  • Mijauti Satosi
  • Josida Kejiti
  • Asari Akira
RU2173154C2
ANTICOAGULANT DRUG, WHICH IS A SYNTHETIC DIPEPTIDE Ac-Trp-Arg-Pip·HCl, A PHARMACEUTICAL COMPOSITION COMPRISING SAID ANTICOAGULANT DRUG 2019
  • Voyushina Tatyana Lvovna
  • Dubovskaya Svetlana Igorevna
  • Puchnina Svetlana Vladimirovna
  • Sokolenko Nikolaj Ivanovich
  • Yarotskij Sergej Viktorovich
RU2712194C1
POLYPEPTIDES OR THEIR SALTS, PHARMACEUTICAL COMPOSITION SHOWING ANTIVIRAL ACTIVITY WITH RESPECT TO HUMAN IMMUNODEFICIENCY VIRUS 1991
  • Nobutaka Fudzii[Jp]
  • Naoki Jamamoto[Jp]
RU2073685C1

RU 2 153 506 C2

Authors

Akikazu Takada

Dzjuniti Onaja

Mikio Arai

Satosi Mijauti

Mamoru Kiogasima

Kejiti Esida

Dates

2000-07-27Published

1994-09-30Filed