FIELD: biotechnology, molecular biology, genetics, medicine, veterinary science. SUBSTANCE: method involves the use of oligo- or polynucleotides containing the modified nitrogen bases, in part, 5-methyldeoxycytidine and 2-aminoadenine. EFFECT: enhanced effectiveness of method as result of two or more bases change with chemically modified ones. 3 cl, 2 tbl
Title |
Year |
Author |
Number |
METHOD OF GENOME DACTYLOSCOPY |
1993 |
- Sverdlov E.D.
- Potapov V.K.
- Veselovskaja S.V.
- Mjasnikov V.A.
- Limborskaja S.A.
- Prosnjak M.I.
- Efremova E.Ju.
|
RU2093582C1 |
METHOD OF DETECTION OF DIFFERENTIALLY EXPRESSING TEMPLATE RNAS AND CLONING THE CORRESPONDING CDNA FRAGMENTS |
1994 |
- Beljavskij A.V.
- Ivanova N.B.
|
RU2111254C1 |
COMPOSITIONS AND METHODS FOR CHEMICAL CLEAVAGE AND REMOVAL OF PROTECTION FOR SURFACE-BOUND OLIGONUCLEOTIDES |
2019 |
- Wu, Xiaolin
- Smith, Randall
- Shieh, Peyton
- Beierle, John M.
- George, Wayne N.
- Lawrence, Elliot John
- Mao, Jie
- Liu, Xiaohai
|
RU2766688C2 |
METHOD FOR INTEGRATION OF MULTIPLE POLYMERASE REACTIONS OF AMPLIFICATION WITH FOLLOWING ANALYSIS OF AMPLIFIED SEQUENCES ON BIOCHIP DIRECTLY |
2001 |
- Mirzabekov A.D.
- Tillib S.V.
- Strizhkov B.N.
|
RU2218414C2 |
HIGH THROUGHPUT SEQUENCING OF POLYNUCLEOTIDE LIBRARIES AND TRANSCRIPTOME ANALYSIS |
2018 |
- Goldfless, Stephen Jacob
- Briggs, Adrian Wrangham
- Chari, Rajagopal
- Jiang, Yue
- Hause, Ronald
- Vigneault, Francois
|
RU2790291C2 |
METHOD OF PARTIAL DNA SEQUENCING FOR DETECTION OF MUTATIONS IN SHORT FRAGMENTS OF SINGLE-STRANDED DNA USING MICROCHIP |
2001 |
- Mirzabekov A.D.
- Vasiliskov V.A.
- Stomakhin A.A.
|
RU2206615C1 |
COMPOSITION FOR IMMOBILIZATION OF BIOLOGICAL MACROMOLECULE IN HYDROGEL, METHOD FOR PREPARING COMPOSITION, BIOCHIP, METHOD FOR CARRYING OUT POLYMERASE CHAIN REACTION (PCR) ON BIOCHIP |
2001 |
- Mirzabekov A.D.
- Rubina A.Ju.
- Pan'Kov S.V.
- Perov A.N.
- Chupeeva V.V.
|
RU2206575C2 |
METHOD OF ANALYSIS OF SOMATIC MUTATIONS IN GENES EGFR, KRAS AND BRAF USING LNA-BLOCKING MULTIPLEX PCR AND SUBSEQUENT HYBRIDISATION WITH OLIGONUCLEOTIDE BIOLOGICAL MICROCHIP (BIOCHIP) |
2014 |
- Emel'Janova Marina Aleksandrovna
- Nasedkina Tat'Jana Vasil'Evna
- Ljubchenko Ljudmila Nikolaevna
- Zasedatelev Aleksandr Sergeevich
|
RU2552483C1 |
METHOD OF ASSAY OF SINGLE BASE EXCHANGES IN MYCOBACTERIUM DNA, METHOD OF DIAGNOSIS OF RESISTANCE OF MYCOBACTERIUM TO RIFAMPICIN, BIOCHIP FOR REALIZATION OF THESE METHODS |
2000 |
- Mirzabekov A.D.
- Mikhajlovich V.M.
- Sobolev A.Ju.
- Grjadunov D.A.
- Lapa S.A.
|
RU2175015C1 |
METHOD OF PERFORMING MANIPULATIONS WITH NUCLEIC ACID SEQUENCE, APPARATUS FOR PERFORMING MANIPULATIONS WITH NUCLEIC ACID SEQUENCE, FLOW VESSEL, SOLID SUPPORT FOR IMMOBILIZATION OF NUCLEIC ACID SEQUENCE, SOLID SUPPORT, AND A METHOD OF PREPARING SUPPORT FOR IMMOBILIZATION OF NUCLEIC ACID SEQUENCE |
1992 |
|
RU2186852C2 |