FIELD: pharmacology, medicine. SUBSTANCE: derivatives of dibenz[b,f] [1,4] -oxazepine-11-on having common formula where p is integer from 1 to 3; each of R1 and R2 are independently hydrogen atom or acyl group R6CO; R3 is hydrogen atom or chlorine atom; R4 and R5 are independently (C1-C6) alkyl; and their pharmaceutically acceptable acid additive salts. EFFECT: changed multimedicinal resistance of antitumor drugs. 18 cl, 2 tbl
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