FIELD: veterinary science. SUBSTANCE: preparation has, mg/ml: histamine, 0.00005-0.0001; copolymer of vinylpyrrolidone and organic acid as a carrier, 0.00154-0.0611; and solvent, the balance. Solvent: physiological solution or its mixture with oily adjuvant at ratio = 1:1, or with 3-5% an aqueous suspension of silica at ratio 1:1. Preparation is prepared by conjugation of histamine with an organic acid link in composition of copolymer with vinylpyrrolidone. For prophylaxis preparation is injected to animals by intramuscular route: to piglets 7-10 days before weakling at volume 1-2 ml (one dose), 14-20 days before weakling at 6-8 days interval at volume 1-2 ml per each injection; to calves - at volume 2-3 ml to one day newborns. Preparation is used for nonspecific immunostimulating prophylaxis of allergotoxicosis in piglets and calves. EFFECT: improved preparation stability, enhanced effectiveness of prophylaxis, simplified procedure. 10 cl, 23 tbl
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Authors
Dates
1997-08-27—Published
1995-10-16—Filed