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2 173 560

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IPC

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Application

2000125713/13, 2000-10-16

(24)

Start date

2000-10-16

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Actual filing date

2000-10-16

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Published

2001-09-20

(72)

Inventor

Rusaleev V.S.Gnevashev V.M.Pruntova O.V.Gusev A.A.Seliverstov V.V.

(73)

Holder

Vserossijskij Nauchno-Issledovatel'Skij Institut Zashchity Zhivotnykh

METHOD OF PREPARING VACCINE PREPARATION AGAINST INFECTIOUS DISEASES OF BACTERIAL ETIOLOGY IN ANIMALS AND BIRDS Russian patent published in 2001 - IPC

Abstract RU 2173560 C1

FIELD: veterinary science, microbiology. SUBSTANCE: cultured suspension of at least one pathogen of bacterial infection is subjected for inactivation with aminoethylethyleneimine. Amino- -ethylethyleneimine is added to pathogen culture up to concentration 0.5-4.0% and mixture is incubated for 12-16 h at 37-38 C. After termination of inactivation antigen is precipitated by centrifugation and antigen concentrate is diluted with sucrose-gelatin mixture. Then antigen is combined with oily adjuvant taken in the ratio 1: 1 and for preparing vaccine preparation antigen is used in the amount providing stimulation of active immune response reaction in body of animals and birds after administration of the end preparation. EFFECT: enhanced immunogenic activity and specific safety of preparation, decreased cost of its making. 7 cl, 3 tbl

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RU 2 173 560 C1

Authors

Rusaleev V.S.

Gnevashev V.M.

Pruntova O.V.

Gusev A.A.

Seliverstov V.V.

Dates

2001-09-20—Published

2000-10-16—Filed

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