FIELD: organic chemistry. SUBSTANCE: invention describes diphenylmethylpiperazine derivatives of the formula: where: R - group of formula
or
. Reagent 1: 1-(diphenylmethyl)-4-[1-(2,3-epoxy)-propyl] -hyperazine. Reagent 2: 1,2,3,4-tetrahydroisoquinoline or [4-(4-chlorophenyl)-4-hydroxy]-piperidine. Reaction conditions: at heating, in o-dichlorobenzene. Synthesized compounds were used in medicine, in cardiology. EFFECT: improved method of synthesis. 1 tbl
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Authors
Dates
1997-09-27—Published
1991-07-10—Filed