FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry and specifically to a heterocyclic compound of formula (I), where
is:
is:
,
and X is CH or N; or a pharmaceutically acceptable salt thereof. Invention also relates to specific compounds, a pharmaceutical composition and an FXIa inhibitor, based on the compound of formula (I), use of said compounds and a method of preventing and / or treating thromboembolic disease.
EFFECT: technical result is obtaining a novel heterocyclic compound having FXIa inhibition effect.
14 cl, 3 dwg, 4 tbl, 46 ex
или - or
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Authors
Dates
2019-12-02—Published
2015-12-09—Filed