FIELD: medicine. SUBSTANCE: present invention describes compound of formula (I) in which Z is hydrogen or halogen; Q is CORI or 5- or 6- membered aryl which contains 1 or 2-heteroatoms from N, O and S optionally substituted or condensed wherein R is hydrogen or CI-methyl (cis-configuration); RI is CI-6 alkyl or aromatic ring which contains heteroatoms O or S and is substituted or condensed with optionally substituted benzene ring; R2 is hydrogen or CI-6-alkyl, and R3 is as defined in claim 1, and enantiomers or salts thereof, methods of preparation of said compounds, drugs based thereon, and also method of medical treatment of central nervous system diseases when using said compounds. EFFECT: more efficient preparation method. 16 cl, 1 tbl
Title |
Year |
Author |
Number |
DERIVATIVES OF CHROMAN OR THIOCHROMAN AND METHODS OF THEIR SYNTHESIS (VARIANTS) |
1990 |
- Lars-Gjunnar Larsson[Se]
- Rol'F Noren[Se]
- Ljusi Anna Reni[Se]
- Svante Bertil Ross[Se]
- Daniel' Dungann Sonn[Se]
- B'Ern Ehrik Svensson[Se]
- Set Olov Torberg[Se]
|
RU2092483C1 |
S-ENANTIOMER OF SUBSTITUTED 2-AMINOTETRALINE, METHODS OF ITS SYNTHESIS AND PHARMACEUTICAL COMPOSITION SHOWING PROPERTY OF 5- RECEPTOR ANTAGONIST |
1990 |
- Uli Khaksell[Se]
- Sven-Ehrik Khillver[Se]
|
RU2086537C1 |
2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALENES OR 3-AMINO- CHROMANES SUBSTITUTED IN RING |
1994 |
- Krejg Stiven Khekhstetter[Us]
- Dajan Linn Kh'Juser[Us]
- Dzhon Menert Skaus[Us]
- Robert Daniehl' Tajtus[Us]
|
RU2105756C1 |
RING SUBSTITUTED 2-AMINO-1,2,3,4-TETRAHYDRO NAPHTHALENES OR 3-AMINOCHROMATES OR THEIR PHARMACEUTICALLY ACCEPTABLE ACID ADDITIVE SALTS AND METHOD FOR THEIR PRODUCTION |
1992 |
- Krejg Stiven Khekhstetter[Us]
- Dajan Linn Kh'Juser[Us]
- Dzhon Menert Skaus[Us]
- Robert Daniehl' Tajtus[Us]
|
RU2057751C1 |
COMPOUNDS (R)-5-CARBAMOYL-8-FLUORO-3,N,N-DISUBSTITUTED AMINO-3,4-DIHYDRO-2H-1-BENZOPYRANES, PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT OF PATIENTS AND METHODS OF SYNTHESIS OF COMPOUNDS |
1994 |
- Dzhon Lesli Ivenden
- Ehva Marija Khammarberg
- Khans Sverker Khansson
- Sven Ehrik Khell'Berg
- Lars Georg Iokhansson
- Jokhan Rune Mikhaehl' Lundkvist
- Svante Bertil' Ross
- Deniehl Dungan Son
- Set Olov Torberg
|
RU2142951C1 |
DERIVATIVES OF 1,2,3,4-TETRAHYDRONAPHTHALENE, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF TREATMENT |
1998 |
- Berg Stefan
- Linderberg Mats
- Ross Svante
- Torberg Set-Olov
- Ul'Ff Bengt
|
RU2194696C2 |
USE OF ISOXAZOLE DERIVATIVES FOR TREATMENT OF PATIENTS WITH IRRITABLE BOWEL SYNDROME (MUCOUS COLITIS) AND A PHARMACEUTICAL COMPOSITION |
1993 |
- Dzhehsvont Singkh Gidda
- Dzhon Menert Skaus
|
RU2127111C1 |
BICYCLIC DERIVATIVES OF ISOTHIOUREA, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
1996 |
|
RU2157802C2 |
THROMBIN INHIBITORS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF, METHOD OF TREATMENT, METHOD OF THEIR SYNTHESIS (VERSIONS) AND PROTECTED DERIVATIVE |
1996 |
- Gustafsson David
- Njustrem Jan-Ehrik
|
RU2176645C2 |
THROMBIN INHIBITOR-CONTAINING AQUEOUS SOLUTION FOR NONPARENTERAL ADMINISTRATION SHOWING STABILITY AT STORAGE |
1995 |
- Ulla St'Ernfel'T
- Mats Sundgren
|
RU2164803C2 |