STRAIN OF HYBRID CULTURED CELLS MUS MUSCULUS L USED FOR PREPARING MONOCLONAL ANTIBODY RAISED TO L-CHAINS OF IMMUNOGLOBULINS Russian patent published in 1997 - IPC

Abstract RU 2093572 C1

FIELD: veterinary biotechnology, immunology. SUBSTANCE: invention relates to preparing the strain of hybrid cultured murine cells producing monoclonal antibodies raised to the light chains of pig immunoglobulins. Strain is obtained by fusion of murine splenocytes of the strain Balb/c immunized with the surface pig IgA with myeloma Sp 2/O cells. Antibodies relate to isotype IgG1 and stimulate precipitating activity of monoclonal antibodies to pig IgG. Invention can be used for development of diagnostic reagents for detection of immunoglobulins in pig biological fluids. EFFECT: strain indicated above, enhanced effectiveness of detection. 2 tbl

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RU 2 093 572 C1

Authors

Verkhovskij O.A.

Fedorov Ju.N.

Fedorova I.P.

Dates

1997-10-20Published

1995-03-31Filed