FIELD: organic chemistry. SUBSTANCE: products: fused heterocyclic compounds of the formula (I): where: X - O, S or where: R1 - H, C1-C7-alkyl, C7-C10-aralkyl, C2-C8-alkylcarbonyl; R2 - H, C7-C10-aralkyl; A - benzene ring; K = 0-3; m = 0-5; n = 2, or its salt. Reagent 1: compound of the formula (II) where: Y - halide; Z - N-protective group. Reagent 2: compound of the formula (III) . The synthesized compounds were used as choline esterase inhibitors. EFFECT: improved method of synthesis. 21 cl, 18 tbl
Authors
Dates
1997-11-10—Published
1991-11-21—Filed