FIELD: biotechnology, veterinary microbiology. SUBSTANCE: vaccine has a synergistic association of limb ILLNESS infectious pathogens inactivated with formalin as antigens of the following strains: Bacteroides nodosus ВИЭВ N ПП-82/90, Fusobacterium necrophorum ВГНКИ N "Кр-1" - DEP and/or Fusobacterium necrophorum ВГНКИ N "Tula" - DEP, Actinomyces (Corynebacterium) pyogenes ВГНКИ N 4/2334 - DEP, Staphylococcus aureus ВГНКИ N 7315 - DEP, Clostridium perfringens of type A ВГНКИ N 28 - DEP and also anatoxin from the strain Clostridium perfringens of type A ВГНКИ N 28 - DEP, adjuvant (aluminium hydroxide or oily adjuvant) and saline solvent (physiological solution). Vaccine provides the lasting and expressing immunity for control over sheep limb ILLNESS caused by different pathogen associations. EFFECT: enhanced effectiveness of vaccine. 6 cl
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