FIELD: veterinary science, microbiology, vaccines, biotechnology. SUBSTANCE: mixed vaccine has a clostridious component as Clostridium perfringens N 3 producing B-toxin of type C actively. It has a complex escherichiosis component consisting of a set of polysaccharide antigens O, K, adhesive antigens, TL- and TC-anatoxins taken at the ratio 1:1. Vaccine provides broad pattern of immunogenetics against enterotoxemia and escherichiosis in piglets at two-fold vaccination of pregnant pigs. The use of the mixed vaccine decreases labor intensity by two-fold, injection numbers and time required for vaccination as compared with the use of monovaccine. EFFECT: enhanced effectiveness. 1 tbl, 3 ex
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