STEROIDS, A METHOD OF SYNTHESIS OF STEROIDS, A METHOD OF SYNTHESIS OF 16-METHYLENESTEROIDS, COMPOUNDS Russian patent published in 1997 - IPC

FIELD: organic chemistry, steroids. SUBSTANCE: product: steroids of the general formula (I) given in description where is a system 3-ketoΔ⁴ or 3-keto-Δ^1,4, or system 3-OR₄•Δ⁵, where R₄ - hydrogen atom or group protecting hydroxyl radical; R - methyl, CH₂OH or CH₂OR′ where R′ - group protecting hydroxyl radical; R₁ and are similar or different, phenyl, pyridyl, thiazolyl or benzothiazolyl radical; R₁ and are similar or different; m = 0 or 1; R₂ and R₃ - hydrogen atom or R₂ - fluorine atom and R₃ - formylhydroxy or acetylhydroxy; line --- at position 9(11) means possible double bond. Product is synthesized by multistage method involving stages of thioalkylation and oxidation of thioalkyl group. The end product is used for synthesis of intermediate compounds used for synthesis steroid preparations. EFFECT: improved method of synthesis. 15 cl