DERIVATIVES OF BENZOFURAZANE OR BENZO-2,1,3-THIADIAZOLE AND METHOD OF TREATMENT Russian patent published in 2002 - IPC

Abstract RU 2189984 C2

FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention elates to derivatives of benzofurazane or benzo-2,1,3-thiadiazole of the formula (I) where R1 means oxygen or sulfur atom; R2 and R3 are taken independently among the group comprising of CR=; M means =CR4 where R4 means independently R; R8 means hydrogen atom; R5 is taken among the group comprising of CR=CR1-, CR=CX-, -(RR1)n-; R7 is taken among the group comprising of -(CRR1)n-, -C(O)-, -CRX-, -CXX1-; R6 is taken among the group comprising of -(CRR1)m-, -C(O)-, -CRX-, CXX1, -S- and O-. Compounds show properties enhancing AMPA-receptors. These compounds can be used for some therapeutic aims, for example, alleviation of behavior learning, for treatment of states, for example, memory disorders caused by decrease amount or efficiency of AMPA-receptors or synapsis using these receptors. Invention describes also a method of treatment using the claimed compounds. EFFECT: improved method of treatment, valuable medicinal properties. 30 cl, 3 dwg, 1 tbl, 22 ex

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RU 2 189 984 C2

Authors

Rodzhers Gehri A.

Marrs Kristofer M.

Dates

2002-09-27Published

1998-02-13Filed