PROCESS FOR PREPARING DIDESOXYDIDEHYDROCARBOCYCLIC NUCLEOSIDES Russian patent published in 1996 - IPC

Abstract RU 2067097 C1

FIELD: as antiviral agents. SUBSTANCE: product: didesoxydidehydrocarbocyclic nucleoside of general formula 1: wherein X is H, Hal, NRR1,, -SR, -OR in which R and R1 and H or C1-4 alkyl; Z is H or NH2. Reagent 1: compound II in which X′ is halogen and Z is as defined above: . Reagent 2: formic acid or derivative thereof such as trialkylchloroformate. Reaction conditions: in organic solvent (amides, chlorinated hydrocarbons, ethers, nitriles excess of reagent 2) at 25-150 C. EFFECT: improved properties of the antiviral agents. 5 cl

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RU 2 067 097 C1

Authors

Robert Vins[Us]

Mej Kh'Jua[Cn]

Piter Lesli Majers[Gb]

Richard Storer[Gb]

Dates

1996-09-27Published

1989-01-19Filed