METHOD OF SYNTHESIS OF SUBSTITUTED 3-AMINOPIPERIDINE Russian patent published in 1998 - IPC

Abstract RU 2105001 C1

FIELD: organic chemistry. SUBSTANCE: products: substituted 3-aminopiperidines of the formula (I) where R1 - phenyl or substituted phenyl, C3-C7-cycloalkoxy, hydroxy, amino--C1-C4-alkylamino-C1-C4-alkyl, phenylhydroxy, naphthyl, thienyl, quinolyl; R2- - phenyl. Reagent 1: aminopiperidine of the formula (II) where R2- - phenyl. Reagent 2: aldehyde of the formula R1--CHO. Reaction conditions: in solvent medium, in the presence of reducing agent. The synthesized compounds were used in medicine as antiinflammatory preparations. EFFECT: improved method of synthesis. 10 cl, 1 tbl

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RU 2 105 001 C1

Authors

Terri Dzhehj Rouzen[Us]

Dates

1998-02-20Published

1992-01-14Filed