FIELD: organic chemistry. SUBSTANCE: products: substituted 3-aminopiperidines of the formula (I) 
where R1 - phenyl or substituted phenyl, C3-C7-cycloalkoxy, hydroxy, amino--C1-C4-alkylamino-C1-C4-alkyl, phenylhydroxy, naphthyl, thienyl, quinolyl; R2- - phenyl. Reagent 1: aminopiperidine of the formula (II) 
where R2- - phenyl. Reagent 2: aldehyde of the formula R1--CHO. Reaction conditions: in solvent medium, in the presence of reducing agent. The synthesized compounds were used in medicine as antiinflammatory preparations. EFFECT: improved method of synthesis. 10 cl, 1 tbl
| Title |
Year |
Author |
Number |
| HYDROGENATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, DERIVATIVES OF PYPERIDINE, PHARMACEUTICAL COMPOSITION AND METHOD FOR SUPPRESSING ACTIVITY OF P COMPOUND IN ORGANISM |
1991 |
- Manodzh S.Desaj[In]
- Terri Dzh.Rosen[Us]
|
RU2105758C1 |
| PYRIDINE DERIVATIVES AND PROCESS FOR PREPARATION THE SAME |
1992 |
- Majkl Denniz Godek[Us]
- Sehlli Gat Raggeri[Us]
- Terri Dzhehj Rouzen[Us]
- Levin T.Uint[Us]
|
RU2081112C1 |
| FLUOROALKOXYBENZYLAMINE DERIVATIVES OF NITROGEN-CONTAINING HETEROCYCLES, PHARMACEUTICAL COMPOSITION, METHOD OF INHIBITION OF SUBSTANCE P EFFECT IN MAMMALIAN |
1992 |
- Dzhon Adams Lou Iii
- Terri Dzhehj Rouzen
|
RU2114848C1 |
| SUBSTITUTED BENZYLAMINOPIPERIDINES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, METHOD OF TREATMENT AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
1996 |
- Satake Kunio
- Sisido Judzi
- Vakabajasi Khiroaki
|
RU2152930C2 |
| PYRROLIDINYL DERIVATIVES OF HYDROXAMIC ACID, METHOD OF PREPARATION THEREOF, INTERMEDIATES, METHOD OF PREPARATION THEREOF (VERSIONS), METHOD OF TREATMENT |
1996 |
|
RU2144917C1 |
| N-HYDROXYLUREAS AS ANTI-INFLAMMATORY AGENTS |
1995 |
- Ando Akemi
- Stivens Rodni V.
|
RU2152935C2 |
| SYNERGETIC TREATMENT OF PARKINSONISM |
1995 |
- Bertran L. Chenard
- Frank S. Menniti
|
RU2176145C2 |
| SUBSTITUTED N-(INDOLE-2-CARBONYL)-BETA-ALANYLAMIDES AND THEIR DERIVATIVES, METHOD OF TREATING GLYCOGENPHOSPHORYLAZO-DEPENDENT DISEASES, METHOD FOR PREVENTING ISCHEMIC MYOCARDIUM DAMAGES, AND PHARMACEUTICAL COMPOSITIONS |
1996 |
- Bernard Kh'Julin
- Judit Li Tredvej
- Vill'Jam Kholt Martin
- Dennis Dzhej Khuver
|
RU2159613C2 |
| SUBSTITUTED 3-AMINOQUINUCLIDINES |
1992 |
- Fumitaka Ito[Jp]
- Tosikhide Kokura[Jp]
- Masami Nakane[Jp]
- Kunio Satake[Jp]
- Khiroaki Vakabajasi[Jp]
|
RU2092486C1 |
| ARYLHYDROXYCYCLOALKENYL- AND ARYLHYDROXYIMINOCYCLOALKENYLHYDROXYUREAS AND PHARMACEUTICAL COMPOSITION INHIBITING ACTIVITY OF 5-LIPOXYGENASE |
1995 |
- Akiesi Kavai
- Makoto Kavai
- Rodni V.Stivens
|
RU2119479C1 |
