N-HYDROXYLUREAS AS ANTI-INFLAMMATORY AGENTS Russian patent published in 2000 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of N-hydroxylurea of the formula (I) or their pharmaceutically acceptable salts where A is C_1-4-alkylene, CH(R), CH(R)-CH₂ or CH(R)-CH₂CH₂; R is methyl or ethyl; m = 1; n = 0 or 1; R¹, R² are hydrogen atom, C_1-4-alkyl or C_2-6-alkenyl; X means O or S; Y means O, C≡C; Ar¹ means phenyl or phenyl monosubstituted with halogen atom; Ar² means phenylene, pyridylene or phenylene monosubstituted with halogen atom, C_1-4-alkyl, C_1-4-alkoxy-group. These compounds can be used for treatment of allergic or inflammatory state in mammalian. EFFECT: valuable medicinal properties of compounds. 11 cl, 1 tbl, 40 ex