ANTIMICROBIAL PHENYLOXAZOLIDINONES Russian patent published in 1999 - IPC

Abstract RU 2134692 C1

FIELD: pharmaceutical industry. SUBSTANCE: described are new phenyloxazolidinone derivatives of general formula I: R7 wherein Q is selected from formula i: OR7, ii: R7, iv: C1-C8 and v: NR8R9, R8 and R9 is hydrogen, C1-C8 wherein C1-C8 is hydrogen, fluorine, C1-C8 alkyl R2 wherein C1-C6 are R3 alkyl which is substituted by fluorine, C1-C3 acyl which is substituted by hydroxy, R4 alkoxy, benzoyl, R5 is hydrogen, hydroxy group, OR wherein R is C1-C8 alkyl; C3-C6 is hydrogen, R6 alkyl NR10 is fluorine; R10 is OR7 alkyl which is substituted by one to three substituents selected from fluorine, chlorine, R7 cycloalkyl; O(CH2)mO is oxygen, wherein is wherein is as defined above, n is 0 or 1, and m is 2 or 3, and pharmaceutically acceptable salts thereof. Compounds of formula I show antimicrobial activity. EFFECT: improved properties of the title compounds.

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RU 2 134 692 C1

Authors

Duglas K.Khatchinson

Majkl R.Barbachjan

Mikio Taniguti

Kietaka Munesada

Khiroesi Jamada

Stiven Dzh.Brikner

Dates

1999-08-20Published

1995-09-12Filed