FIELD: pharmaceutical industry. SUBSTANCE: described are new phenyloxazolidinone derivatives of general formula I: R7 wherein Q is selected from formula i: OR7, ii: R7, iv: C1-C8 and v: NR8R9, R8 and R9 is hydrogen, C1-C8 wherein C1-C8 is hydrogen, fluorine, C1-C8 alkyl R2 wherein C1-C6 are R3 alkyl which is substituted by fluorine, C1-C3 acyl which is substituted by hydroxy, R4 alkoxy, benzoyl, R5 is hydrogen, hydroxy group, OR wherein R is C1-C8 alkyl; C3-C6 is hydrogen, R6 alkyl NR10 is fluorine; R10 is OR7 alkyl which is substituted by one to three substituents selected from fluorine, chlorine, R7 cycloalkyl; O(CH2)mO is oxygen, wherein is wherein is as defined above, n is 0 or 1, and m is 2 or 3, and pharmaceutically acceptable salts thereof. Compounds of formula I show antimicrobial activity. EFFECT: improved properties of the title compounds.
Authors
Dates
1999-08-20—Published
1995-09-12—Filed