BICYCLIC OXAZINE- OR THIAZINE-OXAZOLIDINONES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND METHODS OF TREATMENT OF PATIENTS WITH MICROBIAL INFECTIONS Russian patent published in 1999 - IPC

Abstract RU 2128660 C1

FIELD: organic chemistry, medicine. SUBSTANCE: invention relates to compounds of the formula (I) and formula (II) where X means O, S, SO2,, SO; R1 means independently H, F; R2 means hydrogen atom, C1-C8-alkyl possibly substituted with one or more substituents taken from a group involving F, Cl, hydroxy-group, C1-C8-alkoxy-group; a = 0-3; b = 0-2; c = 0-2 (at condition that b and c both can not be = 0); d = 0-2, and e = 0-2 (at condition that d and e both can not be = 0), or their pharmaceutically acceptable salts and methods of treatment of patients with microbial infections on the basis of compounds proposed. Invention can be used in medicine against human and animal pathogens including gram-positive aerobic bacteria and aerobic organisms. EFFECT: improved method of synthesis, enhanced effectiveness of compounds. 15 cl, 1 tbl, 7 ex

Similar patents RU2128660C1

Title Year Author Number
RING-SUBSTITUTED PHENYLOXAZOLIDINONES WITH HETEROAROMATIC RINGS AS ANTIBACTERIAL AGENTS 1996
  • Duglas K. Khatchinson
RU2154645C2
OXAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS BASED ON THEREOF 1998
  • Khester Dzhekson B. Ml.
RU2215740C2
ANTIMICROBIAL PHENYLOXAZOLIDINONES 1995
  • Duglas K.Khatchinson
  • Majkl R.Barbachjan
  • Mikio Taniguti
  • Kietaka Munesada
  • Khiroesi Jamada
  • Stiven Dzh.Brikner
RU2134692C1
METHOD OF SYNTHESIS OF 5-HYDROXYMETHYL-SUBSTITUTED OXAZOLIDINONES, METHOD OF SYNTHESIS OF 5-AMINOMETHYL-SUBSTITUTED OXAZOLIDINONE AMINES, OXAZOLIDINONE SULFONATE 1997
  • Perlmehn Brjus A.
  • Perro Uill'Jam R.
  • Barbachin Majkl R.
  • Mehnninen Piter R.
  • Tups Dana S.
  • Khauzer Dehvid Dzh.
  • Flek Tomas Dzh.
RU2176643C2
NEW DERIVATIVES OF HYDROXAMIC ACID USEFUL FOR TREATMENT OF PATIENTS WITH DISEASES ASSOCIATED WITH DEGENERATION OF CONNECTIVE TISSUE 1997
  • E. Dzhon Dzhakobsen
RU2168497C2
TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS OR HYDRATES 1993
  • Majkl Robert Barbachin
RU2119484C1
S-OXIDO- AND S,S-DIOXIDOTETRAHYDROTHIOPYRANE PHENYLOXAZOLIDINONES AND METHOD FOR THEIR TESTING 1998
  • Poehl Toni-Dzho
  • Martin Dzhozef P. Ml.
  • Barbachin Majkl R.
RU2205832C2
PHENYLOXAZOLIDINONES HAVING C-C-BOND WITH 4-8-MEMBERED HETEROCYCLIC RINGS 1996
  • Khatchinson Duglas K.
  • Ehnnis Majkl D.
  • Khoffman Robert L.
  • Tomas Richard S.
  • Poel Toni-Dzho
  • Barbachin Majkl Robert
  • Brikner Stiven Dzh.
  • Anderson Dehvid Dzh.
RU2175324C2
PARENTERAL INTRAVENOUS AND PERORAL INTRODUCTION OF OXAZOLIDINONES FOR TREATMENT OF INFECTIOUS FOOT LESIONS IN DIABETES 2003
  • Norden Karl
RU2354372C2
OXAZOLIDINONE ANTIBACTERIAL AGENTS CONTAINING FUNCTIONAL THIOCARBONYL GROUP 1998
  • Khester Dzhekson B. Ml.
  • Najdi Ehldon Dzhordzh
  • Perrikon Sal'Vatore Charl'Z
  • Poel Toni-Dzho
RU2208613C2

RU 2 128 660 C1

Authors

Majkl R.Barbachjan

Richard S.Tomas

Lajza Mari Tomasko

Gehri Dzh.Klik

Robert S.Gehdvud

Dates

1999-04-10Published

1995-10-31Filed