FIELD: organic chemistry, medicine. SUBSTANCE: invention relates to compounds of the formula (I) and formula (II) where X means O, S, SO2,, SO; R1 means independently H, F; R2 means hydrogen atom, C1-C8-alkyl possibly substituted with one or more substituents taken from a group involving F, Cl, hydroxy-group, C1-C8-alkoxy-group; a = 0-3; b = 0-2; c = 0-2 (at condition that b and c both can not be = 0); d = 0-2, and e = 0-2 (at condition that d and e both can not be = 0), or their pharmaceutically acceptable salts and methods of treatment of patients with microbial infections on the basis of compounds proposed. Invention can be used in medicine against human and animal pathogens including gram-positive aerobic bacteria and aerobic organisms. EFFECT: improved method of synthesis, enhanced effectiveness of compounds. 15 cl, 1 tbl, 7 ex
Authors
Dates
1999-04-10—Published
1995-10-31—Filed