CONJUGATE OF DERIVED 14-BROMIDEDAUNORUBICINE WITH MONOCLONAL ANTIBODY OR ITS FRAGMENT WITH ANTITUMOR ACTIVITY AND SPECIFICITY TO THE GIVEN TUMOR; PHARMACEUTICAL COMPOSITION WITH ANTITUMOR ACTIVITY Russian patent published in 1998 - IPC

Abstract RU 2106147 C1

FIELD: medicine, tumor therapy. SUBSTANCE: method deals with elaborating monoclonal antibody conjugates with 14-bromide-4-dimetoxydaunorubicin. At the same time conjugate contains 2-8 molecules of medicine covalently connected with antibody or fragment and developing pharmaceutical composition that contains such a conjugate and also an acceptable diluent or carrier. EFFECT: higher specificity of medicine supply towards tumor. 3 cl, 3 tbl, 19 dwg

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RU 2 106 147 C1

Authors

Jan Fark'Jukhar Kehmpbell Makkenzi[Au]

Dzheffri Allan Piters[Au]

Mark Dzhon Smit[Au]

Dates

1998-03-10Published

1992-06-15Filed