DERIVATIVES OF 5,6-DICHLOROBENZIMIDAZOLE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT AND PROPHYLAXIS OF VIRAL INFECTIONS Russian patent published in 2000 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes new derivatives of 5,6-dichlorobenzimidazole of the general formula (I) where R means hydrogen, halogen atom or -NR¹R² where R¹ means hydrogen atom and R² is taken among the group including hydrogen atom, C_1-6-alkyl, cyano-C_1-6-alkyl, hydroxy-C_1-6-alkyl, halide-C_1-6-alkyl, C_3-7-cycloalkyl, C_2-6-alkenyl, C_3-7-cycloalkyl-C_1-6-alkyl, C_2-6- -alkynyl, phenyl, phenyl-C_1-6-alkyl, 1-pyrrolidinyl-C_1-6-alkyl, -COC_1-6-alkyl, or R¹R² in common with N-atom to which they are bound form 3,4,5- or 6-membered heterocyclic ring, or their pharmaceutically acceptable derivatives taken among the group consisting of carboxylic acids salts or esters. Compounds can be used in medicinal therapy, in part, for treatment and prophylaxis of viral diseases, for example, herpes infections. Invention relates to synthesis of benzimidazole derivatives and pharmaceutical compositions containing thereof and to method of treatment and prophylaxis of viral infections. EFFECT: improved method of synthesis, enhanced antiviral effectiveness of compounds. 18 cl, 47 ex