METHOD OF SYNTHESIS OF (S)-KETOPROFEN Russian patent published in 1998 - IPC

Abstract RU 2119955 C1

FIELD: biotechnology. SUBSTANCE: invention relates to separation of arylalkanoic acids. To obtain (S)-ketoprofen a racemic mixture of enantiomers of ketoprofen ester is subjected for interaction with microorganism Trichosporen laibacchii. Process is carried out at pH 4.5-7.5, at 20-30 C. Method ensures to reach selectivity up to 98%. EFFECT: improved method of synthesis, simplified method, economy. 7 cl, 3 tbl, 6 ex

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RU 2 119 955 C1

Authors

Kristofer Tomas Ivans

Richard Ehntoni Uisdom

Piter Dzhouzef Stehbler

Dzhermano Karganiko

Dates

1998-10-10Published

1992-08-19Filed