CELL-FREE ANTISTAPHYLOCOCCUS VACCINE FOR TREATMENT OF PATIENTS WITH CHRONIC STAPHYLOCOCCUS INFECTION Russian patent published in 1998 - IPC

Abstract RU 2122862 C1

FIELD: medicine, vaccines. SUBSTANCE: invention relates to vaccine consisting of thermolabile and thermostable antigens providing high protective activity of a preparation. The latter is a cell-free antistaphylococcus vaccine involving thermolabile and thermostable protein-polysaccharide antigens from cellular wall of S. aurus, strains N 1991, 1986 exhibiting immunogenicity EД₅₀ = 20-100 mln. microbial cells, virulence ЛД₅₀ = 0.5-2.0 billion microbial cells, low content of protein A and weak allergenic activity. EFFECT: enhanced effectiveness of vaccine, low-reactive property. 7 tbl, 1 ex

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RU 2 122 862 C1

Authors

Efremova V.N.

Egorova N.B.

Masjukova S.A.

Dates

1998-12-10—Published

1995-12-08—Filed