PHARMACEUTICAL COMPOSITION BASED ON INTERCELLULAR ADHESION MEDIATOR (VARIANTS), METHOD OF INHIBITION OF INTERCELLULAR ADHESION, METHOD OF TREATMENT OF PATIENTS WITH INFLAMMATORY DISEASE, METHOD OF ANALYSIS OF THE TEST-COMPOUND WITH RESPECT TO ITS CAPABILITY TO INHIBIT INTERCELLULAR ADHESION, METHOD OF COMPOUND SYNTHESIS Russian patent published in 1998 - IPC

FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention relates to compositions that have at least one component binding with selectin. Selectin-binding components have a general formula: R¹-Gal-1,4-(Fuc-α-1,3-GlcNac-R²)_a-X where R¹ is oligosaccharide or R³-R⁴-C(CO₂H) where R₃ and R₄ can be both similar and distinct - H, -C₁-C₈-alkyl, hydroxyl--C₁-C₈-alkyl, aryl-C₁-C₈-alkyl or alkoxy-C₁-C₈-alkyl where R² is β-1,3-Gal, α-1,2-Man or α-1,6-GalNAc; a = 0 or 1. Compositions can be used for attenuation or control over inflammation and for treatment of patients with inflammatory and other pathological disorders where intercellular adhesion takes part. EFFECT: broadened pattern of agents. 79 cl, 14 ex, 11 dwg, 6 tbl