DERIVATIVE OF INTERCELLULAR ADHESION ICAM-1 SUBSTANCE, DNA SEQUENCE Russian patent published in 1999 - IPC

Abstract RU 2126449 C1

FIELD: molecular biology, biotechnology, medicine. SUBSTANCE: invention proposes a derivative that has five successively located immunoglobulin ICAM-1 domains and a cytoplasmatic domain ICAM-1 or transmembrane domain ICAM-1. DNA encoding a derivative of ICAM-1 is obtained by recombinant procedure. Derivative of ICAM-1 can be used as a highly effective antiinflammatory agent. EFFECT: enhanced effectiveness of a derivative. 3 dwg, 1 tbl, 1 ex

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RU 2 126 449 C1

Authors

Timoti Ehlen Springer

Robert Rotlejn

Stiven Din Merlin

Majkel Loran Dastin

Dates

1999-02-20—Published

1989-09-28—Filed