FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed invention relates to field of molecular medicine and pharmacology and describes liposome, which contains, at last, one lipid bi-layer surrounding water compartment, in which said lipid bi-layer contains, at least, one amphiphilic synthetic pyridinium derivative, in which total amount of amphiphilic pyridinium derivative constitutes from 2 to 25 mol % of total content of lipids in liposome. Liposomes are suitable for delivery of medicinal compounds.
EFFECT: liposome is stable and makes it possible to improve intracellular release of medication.
18 cl, 1 ex, 9 dwg
Title | Year | Author | Number |
---|---|---|---|
LIPOSOMAL COMPOSITIONS USED FOR DRUG DELIVERY | 2015 |
|
RU2757110C2 |
LIPOSOMAL COMPOSITIONS APPLICABLE FOR DRUG DELIVERY | 2005 |
|
RU2574926C2 |
METHOD OF PRODUCING LIPID NANOPARTICLES FOR DRUG DELIVERY | 2012 |
|
RU2647476C2 |
METHOD FOR DELIVERY OF BORON-CONTAINING PREPARATIONS FOR BORON NEUTRON CAPTURE THERAPY | 2014 |
|
RU2589822C2 |
LIPOSOMAL COMPOSITIONS AND SOLID PERORAL MEDICINAL FORMS COMPRISING SUCH COMPOSITIONS | 2018 |
|
RU2751192C2 |
COMPOUNDS FOR TARGETED DELIVERY OF MEDICINE AND ENHANCED SIPHK ACTIVITY | 2012 |
|
RU2632888C2 |
PHARMACEUTICAL COMPOSITION FOR CONTROLLED RELEASE OF WEAK ACID DRUGS AND ITS USE | 2019 |
|
RU2810790C2 |
PHARMACEUTICAL NIOSOMAL GEL BASED ON N-HYDROXY-2-(2-(NAPHTALENE-2-YL)-1H-INDOLE-3-YL)-2-PHENYLACETAMIDE WITH ANTI-TUMOUR ACTIVITY TO GLIOBLASTOMA | 2015 |
|
RU2627449C2 |
LIPOSOMAL COMPOSITION FOR APPLICATION IN PERITONEAL DIALYSIS | 2013 |
|
RU2609860C2 |
TUMOUR TREATMENT AGENT AND KIT CONTAINING LIPOSOMAL GEMCITABINE COMPOSITION | 2016 |
|
RU2761620C2 |
Authors
Dates
2013-05-27—Published
2008-09-05—Filed