FIELD: organic chemistry and technology. SUBSTANCE: method involves an interaction of chlorinated ketone with methylamine an aqueous solution at mole ratio = 1:(2-2.25). A solution of isopropenyl-2-chloropropylketone of the general formula 
is used as chlorinated ketone in methylene chloride and reaction is carried out at 40-45 C, not above. The use of methylene chloride decreases degree of fire-explosion hazard, ensures to decrease duration of the main reaction by about two-fold and eliminate secondary stages of process including steaming, extraction and drying and decrease consumption coefficients by raw. Synthesized compound is used as semiproduct for synthesis of drug - promedol. EFFECT: improved method of synthesis. 1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF SYNTHESIS ALKYLSUBSTITUTED 4-PIPERIDONES | 1993 |
|
RU2044727C1 |
| METHOD OF ALKYLSUBSTITUTED 4-PIPERIODONES SYNTHESIS | 0 |
|
SU1710555A1 |
| PYROTECHNIC AEROSOL-FORMING FIRE-EXTINGUISHING COMPOSITE MATERIAL AND METHOD OF PREPARATION THEREOF | 2000 |
|
RU2185865C1 |
| METHOD OF PRODUCING 16α,17α-CYCLOHEXANO-5α,6α-EPOXYPREGN-3β-OL-20-ONE ACETATE | 2011 |
|
RU2480477C1 |
| METHOD OF PRODUCING POLYPRENYL PHOSPHATES | 2011 |
|
RU2471804C2 |
| PROCESS FOR PREPARING CAROTINOID CONCENTRATE | 1992 |
|
RU2039775C1 |
| METHOD FOR PREPARING 1,2,3,4-TETRACHLOROHEXAFLUOROBUTANE | 2003 |
|
RU2246477C2 |
| METHOD FOR PREPARING NEODYMIUM ORGANIC SALTS (VARIANTS) | 2005 |
|
RU2278107C1 |
| COLORED POLYSILOXANE-POLYCARBONATES AND METHOD FOR THEIR PREPARING | 2005 |
|
RU2278127C1 |
| METHOD OF PRODUCING N-PYRAZINOYL-L-PHENYLALANYL-L-LEUCINE BORONIC ACID OR ANHYDRIDE THEREOF | 2010 |
|
RU2450011C1 |
