FIELD: medicine. SUBSTANCE: method involves taking biopsy sample from antral region of the stomach. Neurohistochemical examination of mucous and submucous layer. Specific features of cholinergic innervation are studied. Focal increased distribution density of cholinergic nerve fibers in mucous and submucous membranes being detected, laparoscopic fundoplication or diaphragmocrurofundopexia with esophagofundography are carried out. No increase in cholinergic nerve fibers density being detected, conservative treatment is carried out. EFFECT: enhanced functional results of treatment. 3 dwg
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