FIELD: gastroenterology. SUBSTANCE: when performing endoscopy and examining biopsy material, in biopsy material of intestinal mucosa determined are: content of neogenic lymph nodules with perifocal fibrosis, presence of dystrophically altered epithelial cells, adhesion of lymphocytes to apical epithelial membrane, and formation of neuromion-like structures. When tetrad of features is found, chrohn's disease is diagnosed. EFFECT: increased accuracy of diagnostics.
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