FIELD: medicine.
SUBSTANCE: method involves applying therapy with 5-aminosalicylic acid combine with anti-inflammatory means. Morphopmetric microcirculation bed examination is carried out before and during treatment but not earlier than in half year from the beginning of treatment course with this preparation. The number of blood vessels, microcirculation bed area, nucleoplasmatic ratio of endothelium cells of microcirculation bed and mean blood vessel lumen diameter is determined in ileal mucous membrane bioptate. Sharp angiogenesis reduction being observed as reduced blood vessels number by52±5%, microcirculation bed area reduction by 24±15%, two-fold increase in nucleoplasmatic ratio of endothelium cells of microcirculation bed witnessing their damage reduction and mean blood vessel lumen diameter increase by 40±8% in combination with reduction of perivascular space edema and infiltration, reduction of exudates in tissue, treatment is estimated as effective one.
EFFECT: high accuracy of estimate.
1 tbl
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Authors
Dates
2006-12-27—Published
2005-03-15—Filed