DERIVATIVES OF BENZOFURANYLALKANE CARBOXYLIC ACID OR A MIXTURE OF THEIR ISOMERS, OR SEPARATE ISOMERS, OR THEIR SALTS Russian patent published in 1999 - IPC

Abstract RU 2125564 C1

FIELD: organic chemistry. SUBSTANCE: invention relates to new derivatives of benzofuranylalkane carboxylic acid of the general formula (I): where R1 - a group of the formula OR3 where R3 - cycloalkyl, 6-membered saturated heterocycle; R2 - free or substituted phenyl; V - alkylene chain; W - tetrazolyl, group COR6 or CONR7R8 where R6R7,R8 - alkyl, cycloalkyl, phenyl, hydrogen. Synthesized compounds show antiinflammatory activity and can be used as drugs for treatment of patients with acute and chronic inflammatory processes. EFFECT: improved method of synthesis, enhanced effectiveness of compounds. 3 cl, 20 tbl, 290 ex

Similar patents RU2125564C1

Title Year Author Number
N-(3-BENZOFURANYL)UREA DERIVATIVES, MIXTURE OF THEIR ISOMERS OR INDIVIDUAL ISOMERS AND THEIR SALTS 1996
  • Gabriehle Brojnlikh
  • Rjudiger Fisher
  • Matsen Ehs-Sajed
  • Rol'F Khenning
  • Mikhaehl' Shpertsel'
  • Karl-Khajnts Shlemmer
  • Ul'Rikh Nil'Sh
  • Stefen Tudkhop
  • Grehkhehm Starton
  • Trivor S. Ehbrem
  • Mehri F. Fitsdzheral'D
RU2162845C2
DERIVATIVES OF CYCLOALKANOINDOLE AND AZAINDOLE, MIXTURE OF THEIR ISOMERS OR SEPARATE ISOMERS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, DERIVATIVES OF CARBOXYLIC ACID AS PARENT COMPOUNDS AND PHARMACEUTICAL COMPOSITION INHIBITING RELEASE OF LIPOPROTEINS ASSOCIATED WITH APOLIPOPROTEIN B-100 1995
  • Ul'Rikh Mjuller
  • Richard Konnell
  • Zigfrid Gol'Dmann
  • Rudi Grjuttsmann
  • Martin Bojk
  • Khil'Mar Bishoff
  • Dirk Dentser
  • Anke Domdej-Bette
  • Shtefan Vol'Fejl'
RU2157803C2
DERIVATIVES OF HETEROCYCLE-SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID, MIXTURE OF THEIR ISOMERS OR SEPARATE ISOMERS AND THEIR SALTS 1994
  • Ul'Rikh Mjuller
  • Jurgen Dressel'
  • Peter Faj
  • Rudol'F Khanko
  • Val'Ter Khjubsh
  • Tomas Krehmer
  • Mattias Mjuller-Glimann
  • Martin Bojk
  • Stanislav Katsda
  • Shtefan Vol'Fejl'
  • Andreas Knorr
  • Jogannes-Peter Stash
  • Zigfrid Tsajss
RU2125990C1
DERIVATIVES OF QUINOLINE CARBOXYLIC ACID, MIXTURE OF ISOMERS OR INDIVIDUAL ISOMERS, THEIR PHARMACEUTICALLY ACCEPTABLE HYDRATES AND SALTS, METHOD FOR THEIR PRODUCTION 1992
  • Uve Petersen[De]
  • Tomas Khimmler[De]
  • Tomas Shenke[De]
  • Andreas Krebs[De]
  • Klaus Grokhe[De]
  • Klaus-Diter Bremm[De]
  • Karl-Georg Mettsger[De]
  • Rajner Ehndermann[De]
  • Khans-Joakhim Tsejler[De]
RU2077533C1
DERIVATIVES OF PYRIDOBENZOXADIAZINE CARBOXYLIC ACID, MIXTURE OF THEIR ISOMERS OR SEPARATE ISOMERS, THEIR PHARMACEUTICALLY USED HYDRATES AND SALTS AND PHARMACEUTICAL COMPOSITION SHOWING ANTIBACTERIAL ACTIVITY ON THEREOF 1995
  • Tomas Jehtsh
  • Burkkhard Mil'Ke
  • Uve Peterzen
  • Tomas Shenke
  • Klaus-Diter Bremm
  • Rajner Ehndermann
  • Karl-Georg Mettsger
  • Martin Sheer
  • Mikhaehl' Shtegemann
  • Khajnts-Georg Vettsshtajn
RU2138504C1
DERIVATIVES OF CYCLOALKANOPYRIDINE, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND INTERMEDIATE COMPOUNDS 1997
  • Shmidt Gunter
  • Brandes Arndt
  • Angerbauer Rol'F
  • Legers Mikhaehl'
  • Mjuller-Glimann Mattias
  • Shmek Karsten
  • Bremm Klaus-Diter
  • Bishoff Khil'Mar
  • Shmidt Del'F
  • Shumakher Joakhim
  • Gira Khenri
  • Paul'Zen Khol'Ger
  • Naab Paul'
  • Konrad Mikhaehl'
  • Shtol'Tefus Jurgen
RU2194698C2
DERIVATIVES OF HETEROCYCLE-SUBSTITUTED PHENYLCYCLOHEXANECARBOXYLIC ACID, MIXTURE OR THEIR ISOMERS OR INDIVIDUAL ISOMERS AND THEIR SALTS 1994
  • Ul'Rikh Mjuller
  • Jurgen Dressel'
  • Peter Faj
  • Rudol'F Khanko
  • Val'Ter Khjubsh
  • Tomas Krehmer
  • Mattias Mjuller-Glimann
  • Martin Bojk
  • Stanislav Katsda
  • Shtefan Vol'Fejl'
  • Andreas Knorr
  • Jogannes-Peter Stash
  • Zigfrid Tsajss
RU2119480C1
DERIVATIVES OF PYRIDOBENZOXADIAZINE, MIXTURE OF THEIR ISOMERS OR SEPARATE ISOMERS, THEIR HYDRATES AND SALTS 1994
  • Tomas Iehtsh
  • Burkkhard Mil'Ke
  • Uve Petersen
  • Tomas Filipps
  • Tomas Shenke
  • Klaus Diter Bremm
  • Rajner Ehndermann
  • Karl Georg Mettsger
  • Martin Sheer
  • Mikhael' Shtegmann
  • Khejnts-Georg Vettsshtejn
RU2131430C1
DERIVATIVES OF THIAZOLOQUINOLINE, THEIR RACEMATES OR SEPARATE ENANTIOMERS AND PHARMACEUTICALLY ACCEPTABLE HYDRATES OR SALTS AND PHARMACEUTICAL COMPOSITION SHOWING ANTIBACTERIAL ACTIVITY 1995
  • Tomas Jehch
  • Verner Khallenbakh
  • Tomas Khimmler
  • Burkkhard Mil'Ke
  • Klaus-Diter Bremm
  • Rajner Ehndermann
  • Frants Pirro
  • Mikhaehl' Shtegemann
  • Khejnts-Georg Vettsshtejn
RU2138505C1
DERIVATIVES OF CYCLOHEXADIENE, MIXTURE OF THEIR ISOMERS OR SEPARATE ISOMERS AND THEIR SALTS AND PHARMACEUTICAL COMPOSITION WITH SELECTIVE MODULATING EFFECT ON CALCIUM-DEPENDENT POTASSIUM CHANNELS OF HIGH CONDUCTIVITY 1995
  • Klaus Urbans
  • Khans-Georg Khejne
  • Bodo Junge
  • Rudol'F Shokhe-Loop
  • Khartmund Vol'Veber
  • Khenning Zommermejer
  • Tomas Glazer
  • Rejlinde Vittka
  • Zhan-Mari-Viktor De Vri
RU2155748C2

RU 2 125 564 C1

Authors

Rjudiger Fisher

Gabriele Brojnlikh

Klaus-Khel'Mut Mors

Rudol'F Khanko

Dzhon-Ehdvard Batler-Rehnsokhoff

Mehzen Ehs-Zajed

Grakhem Sterton

Stiv Tadkhoup

Trevor Ehbrem

Uehndi Mehk Donal'D-Gibson

Dates

1999-01-27Published

1994-05-05Filed