FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes the novel derivatives of cyclohexadiene of the general formula (Ia) 
or (Ib) 
where A is phenyl or unsubstituted naphthyl or naphthyl substituted with 1-3 similar or different residues taken among the group involving nitro-group, halogen atom, trifluoromethyl-group, linear or branched alkyl with 1-6 carbon atoms; R1 is hydrogen atom or linear or branched alkyl with 1-8 carbon atoms; R2 and R3 are similar or different and mean hydrogen atom or linear or branched alkyl with 1-6 carbon atoms; D is linear or branched alkoxycarbonyl with 1-8 carbon atoms, mixture of their isomers or separate isomers and their salts. The above indicated new compounds can be used as an active component of pharmaceutical composition showing selective modulating effect on calcium-dependent potassium channels of high conductivity. EFFECT: new compounds indicated above, valuable pharmacological properties. 4 cl, 3 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
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|
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|
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|
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|
RU2125990C1 |
| METHODS FOR PREPARATION OF 1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID DERIVATIVES IN THE FORM OF R ISOMERS AND THEIR SALTS, STARTING SUBSTANCES AND INTERMEDIATES FOR PREPARATION THEREOF | 1995 |
|
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| N-(3-BENZOFURANYL)UREA DERIVATIVES, MIXTURE OF THEIR ISOMERS OR INDIVIDUAL ISOMERS AND THEIR SALTS | 1996 |
|
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| DERIVATIVES OF BENZOFURANYLALKANE CARBOXYLIC ACID OR A MIXTURE OF THEIR ISOMERS, OR SEPARATE ISOMERS, OR THEIR SALTS | 1994 |
|
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|
RU2162842C2 |
