BIS-PHENYLPIPERAZINE NICOTINIC ACID ESTERS, METHOD OF THEIR SYNTHESIS (VARIANTS), PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT OF PATIENTS WITH CENTRAL NERVOUS SYSTEM DISORDERS Russian patent published in 1999 - IPC

Abstract RU 2127732 C1

FIELD: organic chemistry, medicine. SUBSTANCE: invention describes new compounds of the formula (I) where R is taken from saturated alkyls, cycloalkyls, or a group of the formula (II) where G means CH or nitrogen; m = 0-4; R,R2 and R3 are similar or distinct and taken from hydrogen, halide atoms, C1-C5-alkyl, cyano-, nitro-group, -CO-NH2, or its pharmacologically active salt. New compounds can be used for treatment of patients with central nervous system disorders. Invention describes also a method for synthesis of the above indicated compounds, a pharmaceutical composition based on compound of the formula (I) and a method of treatment of patients with central nervous system disorders using compound of the formula (I). EFFECT: improved method of synthesis, enhanced effectiveness of compounds synthesized. 10 cl, 1 tbl, 5 ex

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RU 2 127 732 C1

Authors

Torb'Ern Lundstedt

Lisbet Abramo

Anders B'Erk

Geran Pettersson

Gunnar Andersson

Kurt Nordvi

Jin Chang Vu

Katarina Ludvig

Ehlisabet Sejfert

Arne Nil'Sson

Dates

1999-03-20Published

1993-06-23Filed